Key result
Dobutamine stress echocardiography was superior to exercise treadmill testing in achieving target heart rate among patients on beta-adrenergic blockade (P<0.001).
Why the study?
The effectiveness of pharmacological versus exercise stress testing in achieving target heart rate among patients on beta-adrenergic blockade was evaluated.
Does dobutamine stress echocardiography improve achieving target heart rate compared to exercise treadmill testing in patients on beta-blockers?
Observational (n=283)
Does dobutamine stress echocardiography improve achieving target heart rate compared to exercise treadmill testing in patients on beta-blockers?
Pharmacological stress testing with dobutamine is superior to exercise stress testing for achieving target heart rate in patients continuing beta-blocker therapy.
Answers are grounded in this paper and cite their sources.
DSE may achieve THR more often than ETT on beta blockers; leaves open whether this improves diagnostic yield or warrants practice change.
Published guidelines recommend continuing beta-adrenergic receptor blockade in patients undergoing stress testing. We evaluated the role of pharmacological versus exercise stress testing in achieving target heart rate (THR) among patients on beta-adrenergic blockade. We compared data from 140 patients who underwent dobutamine stress echo (DSE) and 143 patients who underwent exercise treadmill testing (ETT). In both groups, beta-adrenergic blocker was continued at the time of stress testing. Overall, patients undergoing DSE achieved THR more frequently than ETT. With beta-adrenergic blockade, DSE patients met THR more frequently than ETT patients (p < 0.001). Without beta-adrenergic blockade, there was no difference between either modality in achieving THR. In both DSE and ETT patients, absence of beta-adrenergic blockade increased the odds of achieving THR [odds ratio (OR): 2.46, p = 0.042 and OR: 7.44, p < 0.001, respectively]. Atropine use with DSE increased the odds of achieving THR (OR: 3.76, p = 0.006). In conclusion, pharmacological stress testing appears to be superior to exercise stress testing in achieving THR among patients on beta-adrenergic blockade.
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Sabbath et al. (2005) conducted an observational in Patients on beta-adrenergic blockade undergoing stress testing (n=283). Dobutamine stress echo (DSE) vs. Exercise treadmill testing (ETT) was evaluated on Achieving target heart rate (THR) (p=<0.001). Dobutamine stress echocardiography was superior to exercise treadmill testing in achieving target heart rate among patients on beta-adrenergic blockade (P<0.001).
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