Why the study?
Overlap between chronic coronary artery disease, atrial fibrillation, and heart failure and their impact on secondary prevention and outcomes was not well characterized.
Cohort (n=10,517)
p-value: p=<0.0001
Overlap of chronic coronary artery disease, atrial fibrillation, and heart failure is frequent and associated with incrementally higher mortality despite high rates of guideline-directed secondary prevention.
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Hines et al. (2001) conducted a cohort in Chronic coronary artery disease (CAD), atrial fibrillation (AF) and heart failure (HF) (n=10,517). Disease overlap (CAD, AF, and/or HF) vs. Single disease (CAD alone, AF alone, HF alone) or expected mortality was evaluated on Three-year all-cause and cardiovascular mortality (p=<0.0001).
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