Why the study?
Intracranial hemorrhage in patients taking oral anticoagulants is considered more severe than in those not taking oral anticoagulants, but detailed clinical data are limited.
Does oral anticoagulant use increase the risk of hematoma expansion and surgical intervention in patients with intracranial hemorrhage?
Observational (n=403)
No
Does oral anticoagulant use increase the risk of hematoma expansion and surgical intervention in patients with intracranial hemorrhage?
Answers are grounded in this paper and cite their sources.
Warfarin use is an independent risk factor for hematoma expansion and subsequent surgical intervention in patients with intracranial hemorrhage, highlighting the need for strict observation.
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Hara et al. (2020) conducted an observational in Intracranial hemorrhage (non-traumatic and traumatic) (n=403). Warfarin vs. No oral anticoagulants was evaluated on Hematoma expansion on follow-up CT (OR 4.62, 95% CI 1.77-11.97, p=0.002).
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