Key result
Combined CRP and HMW-adiponectin is linked to more metabolic risk factors than either alone in T2D.
Why the study?
Does the combined measurement of CRP and HMW-adiponectin better reflect metabolic abnormalities than either marker alone in Japanese type 2 diabetic patients?
Population
83 Japanese type 2 diabetic outpatients
Comparison
Combined measurement of serum high-sensitive CRP… vs Measurement of CRP or HMW-adiponectin alone
Design
Cross-sectional
Authors
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Combined CRP/HMW-adiponectin classification was associated with more metabolic risks in T2D; hypothesis-generating, prospective validation required before clinical use.
Cross-Sectional (n=83)
No
Does the combined measurement of CRP and HMW-adiponectin better reflect metabolic abnormalities than either marker alone in Japanese type 2 diabetic patients?
The combined measurement of CRP and HMW-adiponectin may be a useful tool to detect high cardiovascular risk in patients with type 2 diabetes by better reflecting metabolic abnormalities.
Saisho et al. (2008) conducted a cross-sectional in Type 2 diabetes (n=83). Combination of CRP and HMW-adiponectin vs. CRP or HMW-adiponectin alone was evaluated on Association with metabolic risk factors (SBP, glucose, HbA1c, LDL-cholesterol, HDL-cholesterol, triglycerides, and HOMA-IR). The combination of CRP and HMW-adiponectin was significantly associated with a larger number of metabolic risk factors compared with classification by either marker alone in type 2 diabetic subjects.
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