Key result
Carotid IMT and FMD fail to predict acute in-hospital major outcomes in COVID-19.
Why the study?
The prognostic value of carotid intima-media thickness and flow-mediated dilation in patients hospitalized with COVID-19 was uncertain.
Do carotid intima-media thickness and flow-mediated dilation predict acute in-hospital outcomes in patients hospitalized with COVID-19?
Cohort
Do carotid intima-media thickness and flow-mediated dilation predict acute in-hospital outcomes in patients hospitalized with COVID-19?
Carotid IMT and FMD do not independently predict acute in-hospital outcomes in COVID-19 patients, suggesting other risk factors drive clinical outcomes.
Carotid IMT and FMD should not inform acute risk assessment in hospitalized COVID-19; leaves open their prognostic value in other acute illnesses.
Studies have suggested a role of endothelial dysfunction and atherosclerosis in COVID-19 pathophysiology. In this prospective cohort study, we assessed the prognostic value of carotid intima-media thickness (IMT) and flow-mediated dilation (FMD) in patients with COVID-19. Carotid IMT and FMD were not independent predictors of major outcomes. These results suggest that other risk factors may be the main drivers of clinical outcomes in patients with COVID-19.
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Cristina-Oliveira et al. (2022) conducted a cohort in COVID-19. Carotid intima-media thickness (IMT) and flow-mediated dilation (FMD) was evaluated on acute in-hospital major outcomes. Carotid intima-media thickness and flow-mediated dilation were not independent predictors of acute in-hospital major outcomes in patients hospitalized with COVID-19.
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