Key result
Unilateral leg edema reveals the ninth reported case of lymphangiosarcoma in a chronically lymphedematous extremity.
Why the study?
Lymphangiosarcoma has been reported in chronically lymphedematous extremities unrelated to other neoplasms, but cases remain rare.
Case Report (n=1)
This case report describes a rare instance of lymphangiosarcoma in a chronically lymphedematous lower extremity unrelated to another neoplasm.
Supports heightened suspicion for sarcoma in chronic idiopathic lymphedema; extends sparse case reports but remains hypothesis-generating.
IN 1948 Stewart and Treves1described six cases of lymphangiosarcoma in chronically lymphedematous arms following radical mastectomy. Since that time there have been more than 70 cases reported. A similar neoplastic process has also been described in chronically lymphedematous extremities unrelated to any other neoplasm. The following case is the ninth such report. Report of Case On Oct 8, 1962, a 25-year-old white man was seen in the clinic with a complaint of unilateral lower extremity edema. The edema had begun five days previously and had subsided spontaneously. The patient also complained of lumps over his right hip that had existed for two years. There was no pain associated with the edema or the lumps. A history of two previous episodes of edema at ages 13 and 24 was given. The edema always occurred in the right lower extremity and the thigh was described as being hot and inflamed
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John F. Prudden (1967) conducted a case report in Lymphangiosarcoma (n=1). A 25-year-old man presented with unilateral lower extremity edema and lumps over his right hip, representing the ninth reported case of lymphangiosarcoma in a chronically lymphedematous extremity.
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