Key result
Angiotensin II infusion promotes abdominal and thoracic aortic aneurysms in mice to model human disease.
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Enables mechanistic studies of distinct aortic aneurysms in mice; extends preclinical models while leaving human translation open.
Angiotensin II infusion in mice promotes abdominal and thoracic aortic aneurysms, which provides a feasible approach to study the mechanisms of these two distinct diseases.
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Bruemmer et al. (2011) studied this question. Angiotensin II infusion in mice promotes abdominal and thoracic aortic aneurysms, providing a feasible model to study the mechanisms of these distinct human diseases.
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