Key result
Percutaneous closure of multiple ASDs achieves ~99% complete closure at 6 years without further treatment.
Why the study?
The feasibility and long-term outcomes of percutaneous closure of multiple atrial septal defects were not well established.
Is percutaneous closure feasible, safe, and effective in patients with multiple atrial septal defects?
Population
165 patients with multiple ASDs undergoing percutaneous closure
Comparison
Percutaneous closure of multiple ASDs with single vs multiple device implantations
Design
Cohort study
Follow-up
6 +/- 2 years
Authors
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Supports percutaneous closure for multiple ASDs in selected patients; leaves open need for randomized trials versus surgery.
Cohort (n=165)
No
Is percutaneous closure feasible, safe, and effective in patients with multiple atrial septal defects?
Percutaneous closure of multiple atrial septal defects is feasible and highly effective, achieving complete closure in 99% of cases at long-term follow-up without the need for further interventions.
Butera et al. (2010) conducted a cohort in Multiple atrial septal defects (n=165). Percutaneous closure was evaluated on Immediate procedural success and long term safety and efficacy (complete closure). Percutaneous closure of multiple atrial septal defects was feasible, achieving complete closure in 99% of cases at a mean follow-up of 6 years with no need for further treatment.
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