Key result
Marchiafava-Bignami Disease type B presents with an isolated reversible splenial lesion and favorable recovery.
Why the study?
Marchiafava-Bignami Disease is a toxic demyelinating disease with high mortality and variable clinical and MRI presentations that require further characterization.
Case Report (n=1)
Marchiafava-Bignami Disease type B can present with an isolated reversible splenial lesion on MRI and have a favorable clinical recovery.
Answers are grounded in this paper and cite their sources.
May aid recognition of atypical MBD type B; leaves open questions on prognosis and management.
Marchiafava-Bignami Disease (MBD) is a toxic demyelinating disease often diagnosed in chronic alcoholics. The disease process typically involves the corpus callosum and clinically presents with various manifestations resulting in MBD type A and type B on the basis of clinical condition, extent of callosal involvement and extracallosal involvement at brain magnetic resonance imaging (MRI), and prognosis. The death rate is high. We report a patient affected by MBD type B, who presented an isolated reversible splenial lesion at brain MRI and achieved a favorable recovery.
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Muccio et al. (2019) conducted a case report in Marchiafava-Bignami Disease (MBD) type B (n=1). A patient with Marchiafava-Bignami Disease type B presented with an isolated reversible splenial lesion on brain MRI and achieved a favorable recovery.
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