Key result
CMR markers including aortic stiffness and native T1/T2 evaluate CV and HF risk in CKD.
Why the study?
Stratification of cardiovascular risk in patients with chronic kidney disease remains an open question, with aortic stiffness emerging as an important prognostic factor.
Can novel imaging markers (aortic stiffness, native T1, native T2) evaluated by cardiovascular magnetic resonance be used for diagnostic and prognostic purposes in patients with chronic kidney disease?
Can novel imaging markers (aortic stiffness, native T1, native T2) evaluated by cardiovascular magnetic resonance be used for diagnostic and prognostic purposes in patients with chronic kidney disease?
Cardiovascular magnetic resonance evaluation of aortic stiffness and myocardial tissue characterization offers potential diagnostic and prognostic value for cardiovascular risk stratification in patients with chronic kidney disease.
Purpose of Review To provide an update on the recent findings in the field of aortic stiffness and heart failure in patients with chronic kidney disease (CKD). Recent Findings Stratification of cardiovascular risk in CKD remains an open question. Recent reports suggest that aortic stiffness, an independent predictor of cardiovascular events in many patient populations, is also an important prognostic factor in CKD. Also, novel measures of myocardial tissue characterization, native T1 and T2 mapping techniques, have potential as diagnostic and prognostic factors in CKD. Summary Cardiovascular magnetic resonance has the ability to thoroughly evaluate novel imaging markers: aortic stiffness, native T1, and native T2. Novel imaging markers can be used for diagnostic and prognostic purposes as well as potential therapeutic targets in CKD population.
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Gawor et al. (2020) conducted a review in Chronic Kidney Disease and Heart Failure. Cardiovascular magnetic resonance imaging (aortic stiffness, native T1, and native T2 mapping) was evaluated. Cardiovascular magnetic resonance imaging markers, including aortic stiffness, native T1, and native T2, are valuable diagnostic and prognostic tools for evaluating cardiovascular risk and heart failure in patients with chronic kidney disease.
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