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May 23, 2015Archives of Cardiovascular Imaging

Detection of Undiagnosed Ischemic Heart Disease in Hemodialysis Patients Using Myocardial Perfusion Imaging

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Key result

Dipyridamole MPI detects undiagnosed IHD in ~22% of hemodialysis patients.

  • n=69

Why the study?

The prevalence of undiagnosed ischemic heart disease in hemodialysis patients was considerable and needed assessment using myocardial perfusion imaging.

Does dipyridamole myocardial perfusion imaging detect undiagnosed ischemic heart disease in hemodialysis patients?

Comparison

IHD-positive group vs IHD-negative group based on dipyridamole MPI

Design

Cross-sectional descriptive study

Authors

MNMarzieh NikparvarEBElham BoushehriHSHamid Reza Samimagham

Discussion

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Member takes

Overview

May support targeted ischemia screening in high-risk hemodialysis patients; leaves open whether detection improves outcomes.

Study Design

Type

Cross-Sectional (n=69)

Structured PICO

Does dipyridamole myocardial perfusion imaging detect undiagnosed ischemic heart disease in hemodialysis patients?

P
Population
69 hemodialysis patients with a mean age of 52.1 years assessed for undiagnosed ischemic heart disease using dipyridamole myocardial perfusion imaging.
E
Exposure
Dipyridamole myocardial perfusion imaging (MPI) with Tc 99m sestamibi
O
Outcome
Prevalence of undiagnosed ischemic heart disease (IHD)surrogate

Dipyridamole myocardial perfusion imaging reveals a considerable prevalence (21.7%) of undiagnosed ischemic heart disease in hemodialysis patients, particularly those with traditional and uremia-specific risk factors.

Cite This Study

Nikparvar et al. (2015) conducted a cross-sectional in Hemodialysis (n=69). Dipyridamole myocardial perfusion imaging (MPI) was evaluated on Undiagnosed ischemic heart disease (IHD). Dipyridamole myocardial perfusion imaging detected undiagnosed ischemic heart disease in 21.7% of hemodialysis patients, with higher prevalence linked to diabetes, hypertension, and aging (P<0.05).

synapsesocial.com/papers/6aaf934c292bb98df525e4cfhttps://doi.org/10.5812/acvi.29470
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Also Consider

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  3. 3Coronary Artery Disease in End-Stage Renal Disease2003 · 241 citations
  4. 4Kidney Disease as a Risk Factor for Development of Cardiovascular Disease2003 · 3,794 citations