Key result
Tourniquet deflation is linked to a ~10 mmHg transient rise in EtCO2 and decreased MAP.
Why the study?
Hemodynamic and end tidal CO2 changes following tourniquet release in lower limb surgery under general anesthesia are not well characterized.
Does pneumatic tourniquet release cause significant end tidal CO2 and hemodynamic changes in patients undergoing lower limb surgery under general anesthesia?
Observational (n=150)
No
Does pneumatic tourniquet release cause significant end tidal CO2 and hemodynamic changes in patients undergoing lower limb surgery under general anesthesia?
Absolute Event Rate: 41.317% vs 31.316%
p-value: p=<0.0001
Tourniquet deflation during lower limb surgery under general anesthesia is associated with significant transient increases in heart rate and EtCO2, and a decrease in mean arterial pressure.
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Tourniquet deflation is associated with transient EtCO2 rise and MAP drop; leaves open whether monitoring protocols require adjustment in lower limb surgery.
Megha Khetan (2019) conducted an observational in Patients undergoing elective lower limb surgery (n=150). Tourniquet deflation vs. Baseline (during tourniquet inflation) was evaluated on End tidal carbon dioxide (EtCO2) at 5 minutes after tourniquet deflation (p=<0.0001). Tourniquet deflation during lower limb surgery under general anesthesia caused a significant transient increase in EtCO2 to 41.3 mmHg and a decrease in mean arterial pressure to 85.4 mmHg at 5 minutes post-deflation.
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