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Clinical study reveals cisapride improves intestinal motility after colic surgery in horses, indicating efficacy against postoperative ileus.
SUMMARY Cisapride was administered to 42 horses, treated surgically for colic, to prevent the occurrence of post operative ileus. The results of this treatment were beneficial. Only two horses showed gastric reflux in the post operative phase; borborygmi were detected within 3 h after surgery and defaecation within 24 h post operatively. These results were a marked improvement over the usual treatment, especially when colic was due to small intestinal pathology. When colic was related to large intestinal pathology, a less pronounced effect was observed.
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Geest et al. (1991) studied this question.
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