What question did this study set out to answer?

The main aim is to review the pharmacological properties and therapeutic potential of cisapride.

Cisapride: A Gastrointestinal Prokinetic Drug

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Review summarizes efficacy and safety of cisapride in gastrointestinal motility disorders, suggesting it as an alternative treatment.

The main aim is to review the pharmacological properties and therapeutic potential of cisapride.
Conducted a MEDLINE database search for English-language studies on cisapride.
Focus on controlled clinical studies due to high placebo response rates in gastrointestinal complaints.
Extracted data on study design, population, outcomes, and safety from identified publications.
Cisapride was superior to placebo in relieving symptoms of reflux esophagitis, nonulcer dyspepsia, and gastroparesis.
Cisapride showed effects similar to histamine H2-antagonists in treating reflux esophagitis.
It was equal to or superior to metoclopramide but had fewer central nervous system adverse effects.

Barone et al. (1994) studied this question.

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