Key result
VPC-related symptoms are linked to an ~11% higher VPC coupling interval ratio.
Why the study?
Symptoms associated with frequent ventricular premature complexes remain limited and predictors of VPC-related symptoms are not well identified.
Is the coupling interval ratio associated with VPC-related symptoms in patients with idiopathic outflow tract VPCs?
Observational (n=109)
Is the coupling interval ratio associated with VPC-related symptoms in patients with idiopathic outflow tract VPCs?
A higher VPC coupling interval ratio (>50%) is associated with the presence of VPC-related symptoms such as palpitations or dropped beats.
Answers are grounded in this paper and cite their sources.
Higher VPC CI ratio (>50%) may predict palpitations or dropped beats in OT VPCs; leaves open whether this informs symptom management or needs prospective confirmation.
BACKGROUND AND OBJECTIVES: Frequent ventricular premature complex (VPC) is one of the most common arrhythmia syndromes. Symptoms observed frequently with this arrhythmia syndrome remain limited. We sought to identify predictors of VPC-related symptoms by analyzing demographic information, VPC burden, and VPC surface electrocardiogram characteristics. SUBJECTS AND METHODS: We prospectively enrolled 109 patients with idiopathic outflow tract VPCs (63 males, 49±16 years old). They were divided into Group A (n=30, without VPC-related symptoms of palpitations or "dropped beats") and Group B (n=79, with VPC-related symptoms). Measured parameters were sinus and VPC QRS width, coupling interval (CI) between the previous sinus beat and VPC, CI ratio (%, CI/sinus cycle length), post-VPC CI and CI ratio, and VPC amplitude. RESULTS: Both groups had similar age (p=0.22), daily VPC burden (p=0.15), and VPC site of origin (p=0.36). The VPC CI ratio was higher in Group B (60±15%) than in Group A (49±22%) (p=0.01). CONCLUSION: VPC-related symptoms are associated with a higher VPC CI ratio (>50%). The physiologic basis for these results deserves further study.
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Park et al. (2015) conducted an observational in Idiopathic outflow tract ventricular premature complexes (VPCs) (n=109). VPC-related symptoms vs. No VPC-related symptoms was evaluated on VPC coupling interval (CI) ratio (p=0.01). Patients with VPC-related symptoms had a higher VPC coupling interval ratio compared to those without symptoms.
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