Key result
Higher VPC coupling interval ratio is linked to symptomatic idiopathic ventricular premature complexes.
Why the study?
Patients with frequent idiopathic ventricular premature complexes often experience symptoms, but ECG predictors of these symptoms are not well defined.
Cross-Sectional (n=60)
No
Absolute Event Rate: 59.2% vs 41.12%
p-value: p=0.004
Coupling interval ratio may aid symptom risk stratification in idiopathic VPCs; hypothesis-generating and requires prospective validation.
Background and objective:Ventricular premature complexes (VPCs) are the most common arrhythmia encountered in cardiology OPD. Patients with frequent VPCs are often symptomatic. Our study aims to identify the ECG predictors of symptoms in patients with idiopathic VPCs in 24 hours Holter monitoring. Subjects and methods: This study was conducted on 102 patients with VPCs during the period of February 2019 to December 2019 in cardiology OPD of our centre.All the patients were screened with transthoracic echocardiography.24 hours Holter monitoring was done, the measured parameters were QRS width (Both in sinus beat & VPC), coupling interval (CI),CI ratio (CL/sinus cycle length) and VPC burden (Number and percentage of VPCs per day). Results:Both group had similar categorical age group and gender.ORS width of both sinus beat (P = 0.389) and VPCs (P = 0.035), VPC CI (P=0.487) and VPC burden (P = 0.458) did not correlate with symptoms but VPC CI ratio were significantly higher in Group B(symptomatic) than in group A (P = 0.004) Conclusion:There is a relationship between VPC related symptoms and VPC CI ratio.
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Dharmaraj et al. (2020) conducted a cross-sectional in Idiopathic ventricular premature complexes (VPCs) (n=60). Symptomatic ventricular premature complexes vs. Asymptomatic ventricular premature complexes was evaluated on VPC coupling interval (CI) ratio (p=0.004). Patients with symptomatic idiopathic ventricular premature complexes had a significantly higher coupling interval ratio compared to asymptomatic patients (59.20% vs 41.12%, p=0.004).
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