Key result
Genome sequencing of coxsackievirus B3 from a child with acute myocarditis reveals a 7,402-nucleotide genome.
Why the study?
The complete genome sequence of a human coxsackievirus B3 from a child with myocarditis was needed to analyze its evolutionary and epidemic characteristics.
Case Report (n=1)
No
The complete genome sequence of a human coxsackievirus B3 strain from a child with myocarditis was determined, which will aid in analyzing the evolutionary and epidemic characteristics of the virus.
Offers no immediate clinical implications for myocarditis; leaves open whether this genome harbors unique pathogenic features.
A human coxsackievirus B3 (CVB3), designated strain Beijing0811, was isolated from a child diagnosed with hospital-acquired infectious acute myocarditis in Beijing, China, and propagated in human rhabdomyosarcoma cells. The complete genome sequence of this virus was 7,402 nucleotides, excluding the 3' poly(A) tail, which encoded a large polyprotein with 2,185 amino acids. This report will help us to analyze the evolutionary and epidemic characteristics of CVB3.
No takes yet. Share an insight, caveat, or question.
Du et al. (2013) conducted a case report in Hospital-acquired infectious acute myocarditis (n=1). Complete genome sequencing of human coxsackievirus B3 (strain Beijing0811) was evaluated on Complete genome sequence. Complete genome sequencing of a human coxsackievirus B3 isolated from a child with acute myocarditis revealed a 7,402-nucleotide genome encoding a 2,185-amino acid polyprotein.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: