Key result
FMD vaccine with ISA 201 VG yields ~55% higher PD50 versus ISA 206 VG in pigs.
Why the study?
The study aimed to compare the efficacy of swine FMD vaccine emulsified with oil adjuvant ISA 201 VG versus ISA 206 VG to evaluate improvements in cellular responses.
Absolute Event Rate: 15.59% vs 10.05%
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May favor ISA 201 VG for FMD vaccines in pigs; leaves open field efficacy and broader adoption.
Li et al. (2013) studied Foot-and-mouth disease (FMD). FMD vaccine with adjuvant ISA 201 VG vs. FMD vaccine with adjuvant ISA 206 VG was evaluated on Fifty percent of protection dose (PD50). FMD vaccine emulsified with ISA 201 VG yielded a higher fifty percent protection dose (PD50 = 15.59) than the vaccine with ISA 206 VG (PD50 = 10.05) in pigs.
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