Key result
Preoperative CTR >0.6 predicts ~136% higher in-hospital mortality after rheumatic heart disease surgery.
Why the study?
The prognostic value of cardiothoracic ratio in patients with rheumatic heart disease undergoing valve replacement surgery was not well established.
Does a preoperative cardiothoracic ratio >0.6 predict in-hospital and 1-year mortality in patients with rheumatic heart disease undergoing valve replacement surgery?
Cohort (n=1,772)
Does a preoperative cardiothoracic ratio >0.6 predict in-hospital and 1-year mortality in patients with rheumatic heart disease undergoing valve replacement surgery?
Odds Ratio: 2.36
p-value: p=0.005
A preoperative cardiothoracic ratio >0.6 is a simple, independent predictor of in-hospital and 1-year mortality in patients with rheumatic heart disease undergoing valve replacement surgery.
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CTR >0.6 may flag higher-risk RHD valve patients for intensified monitoring; leaves open prospective validation in modern risk models.
Jiang et al. (2018) conducted a cohort in rheumatic heart disease (n=1,772). Cardiothoracic ratio >0.6 vs. Cardiothoracic ratio ≤0.6 was evaluated on in-hospital mortality (OR 2.36, p=0.005). A preoperative cardiothoracic ratio >0.6 independently predicted in-hospital (OR 2.36, P=0.005) and 1-year mortality (HR 2.06, P=0.006) in patients with rheumatic heart disease undergoing surgery.
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