Key result
Obstructive CAD is linked to biatrial remodeling and reduced biatrial ejection fraction vs. healthy controls.
Why the study?
Advances in cardiac imaging with multidetector computed tomography require new criteria for normal atrial volumetric measurements, especially considering sex differences and coronary artery disease status.
Do biatrial volumes measured by MDCT differ by sex and the presence of obstructive coronary artery disease?
Observational (n=686)
Do biatrial volumes measured by MDCT differ by sex and the presence of obstructive coronary artery disease?
MDCT-derived left atrial volumes require sex-specific reference values and are significantly altered in patients with obstructive coronary artery disease.
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CAD patients show higher LA volumes and lower biatrial EF; supports sex-specific norms but leaves open prospective validation for prognosis.
Budoff et al. (2014) conducted an observational in Coronary artery disease (n=686). Obstructive coronary artery disease vs. Healthy individuals with no cardiac abnormalities was evaluated on Biatrial volume, stroke volume, and ejection fraction. Obstructive coronary artery disease was associated with significantly higher left atrial volume, lower right atrial stroke volume, and lower biatrial ejection fraction compared to healthy controls.
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