Key result
Loratadine linked to new-onset ventricular tachycardia resembling torsade de pointes.
Why the study?
Ventricular tachycardia following ingestion of the commonly used antihistamine loratadine has not been well documented.
Answers are grounded in this paper and cite their sources.
Loratadine ingestion may be associated with ventricular tachycardia (torsade de pointes), as documented in a patient with an implanted defibrillator.
This report describes ventricular tachycardia, likely to have been torsade de pointes, following ingestion of the non-sedating antihistamine loratadine. Documentation of the arrhythmia was made possible by the automatic electrogram storage facility of an implanted defibrillator in a patient with no prior history of cardiac arrhythmia.
No takes yet. Share an insight, caveat, or question.
Kuchar et al. (2002) studied this question. Ingestion of the non-sedating antihistamine loratadine was associated with ventricular tachycardia, likely torsade de pointes, in a patient with no prior history of cardiac arrhythmia.
Synapse has enriched 10 related papers. Consider them for comparative context: