Key result
Shear wave elastography showed significantly greater renal cortical stiffness in patients with advanced diabetic kidney disease compared to healthy subjects (23.72 vs 9.02 kPa; P<0.001).
Why the study?
Does shear wave elastography imaging accurately assess chronic pathologic changes and differentiate CKD grades in patients with advanced diabetic kidney disease?
Population
52 participants, comprising 29 diabetic patients with chronic kidney disease grades 3-4 due to diabetic…
Comparison
Combined conventional ultrasound and shear wave… vs Healthy subjects and internal comparison across…
Design
Cross-sectional
Authors
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SWE may offer a noninvasive option for fibrosis assessment in advanced DKD; leaves open whether it can guide management or supplant biopsy.
Observational (n=52)
Does shear wave elastography imaging accurately assess chronic pathologic changes and differentiate CKD grades in patients with advanced diabetic kidney disease?
Absolute Event Rate: 23.72% vs 9.02%
p-value: p=<0.001
Shear wave elastography is a practical, non-invasive method for quantitatively evaluating chronic morphological changes and differentiating CKD grades in advanced diabetic kidney disease.
Hassan et al. (2016) conducted an observational in Diabetic kidney disease (n=52). Advanced diabetic kidney disease vs. Healthy subjects was evaluated on Cortical stiffness (p=<0.001). Shear wave elastography showed significantly greater renal cortical stiffness in patients with advanced diabetic kidney disease compared to healthy subjects (23.72 vs 9.02 kPa; P<0.001).
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