Key result
Higher internal current drain dual-chamber pacemakers are linked to a 7.1% vs 0.7% early exchange rate.
Why the study?
The determinants of dual chamber pulse generators longevity and the reliability of battery impedance measurements to predict end-of-life were not well established.
Does internal current drain and battery capacity affect dual chamber pulse generator longevity in patients requiring pacemakers?
Cohort (n=577)
Does internal current drain and battery capacity affect dual chamber pulse generator longevity in patients requiring pacemakers?
Absolute Event Rate: 7.1% vs 0.7%
p-value: p=< 0.01
Internal current drain is a more important determinant of dual chamber pulse generator longevity than battery capacity, and battery impedance can reliably predict end-of-life.
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Higher current drain was associated with earlier dual-chamber generator exchange; hypothesis-generating for device selection and longevity-focused design.
Markewitz et al. (1995) conducted a cohort in Implantation of dual chamber pulse generators (n=577). Dual chamber pulse generator PG2 vs. Dual chamber pulse generator PG1 was evaluated on Pulse generator exchange due to end-of-life (p=< 0.01). Dual chamber pulse generators with higher internal current drain (PG2) had a significantly higher rate of exchange due to end-of-life compared to PG1 (7.1% vs 0.7%, P<0.01).
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