Key result
Surface ECG characterizes key rhythm and conduction abnormalities in patients with Down syndrome.
Why the study?
Down syndrome is strongly associated with heart disease, the main cause of mortality in the first 2 years of life, and most cardiac abnormalities can be suspected by surface 12-lead ECG analysis.
Systematic Review
This systematic review summarizes available evidence on surface ECG and cardiac rhythm and conduction abnormalities in patients with Down syndrome to aid clinical cardiologists and pediatricians.
Answers are grounded in this paper and cite their sources.
Aids ECG evaluation in Down syndrome patients now; extends synthesized evidence for clinicians and future research.
Down syndrome is the most common chromosomal abnormality, with an incidence of one case in every 650 live births. It is strongly associated with heart disease, which constitutes the main cause of mortality during the first 2 years of life in this population. Most of the cardiac abnormalities in patients with Down syndrome can be suspected by analysing the surface 12-lead ECG. The purpose of this systematic review was to analyse all available published material on surface ECG and cardiac rhythm and conduction abnormalities in patients with Down syndrome to facilitate the search to the clinical cardiologist and paediatrician.
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Caro et al. (2014) conducted a systematic review in Down syndrome. Surface 12-lead ECG was evaluated on Cardiac rhythm and conduction abnormalities. A systematic review of surface ECG and cardiac rhythm and conduction abnormalities in patients with Down syndrome was conducted to facilitate clinical evaluation.
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