Key result
ET-1 mRNA levels in the mouse uterus significantly increased immediately after parturition and gradually decreased to basal levels by day 14 postpartum.
Authors
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Does not support clinical changes in uterine or reproductive care; leaves open ET-1's role in human parturition.
Uchide et al. (2001) studied Pregnancy and post-parturient period. Parturition and postpartum period vs. Estrous cycle or pregnancy was evaluated on ET-1 mRNA levels and cellular distribution of ET-1 peptide. ET-1 mRNA levels in the mouse uterus significantly increased immediately after parturition and gradually decreased to basal levels by day 14 postpartum.
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