Key result
Truncal subcutaneous and visceral fat independently link to lower insulin sensitivity in obese women.
Why the study?
The importance of truncal subcutaneous fat in relation to insulin sensitivity in obese women remains controversial despite known associations of visceral fat with insulin resistance syndrome.
Population
38 white and black obese nondiabetic premenopausal women
Comparison
Visceral fat mass and truncal subcutaneous fat mass in relation to insulin sensitivity and serum triglyceride levels
Design
Cross-sectional study with MRI and DXA fat measurements in a subset
Authors
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Regional fat may contribute to insulin resistance beyond total adiposity in obese women; leaves open causal role and need for prospective trials.
Cross-Sectional (n=38)
p-value: p=<.012
In obese nondiabetic premenopausal women, both visceral fat and truncal subcutaneous fat are independently associated with insulin resistance.
Marcus et al. (1999) conducted a cross-sectional in Obesity (n=38). Truncal subcutaneous fat and visceral fat mass was evaluated on Insulin sensitivity index (S(I)) (p=<.012). Truncal subcutaneous fat and visceral fat mass were independently and negatively related to insulin sensitivity in obese women (P<0.012 and P<0.035, respectively).
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