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May 1, 1969Circulation

Coarctation of the Aorta in Infants and Children

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Key result

Operative coarctation repair shows ~3% mortality in older patients and saves half of critically ill infants.

  • n=333

Why the study?

Early recognition and operative correction of coarctation of the aorta in infants and children are critical to prevent fatal outcomes, but operative mortality and outcomes by age were not well characterized.

Does operative correction improve survival in infants and children with coarctation of the aorta?

Population

333 children with coarctation of the aorta including 179 under one year of age

Comparison

Operative correction in infants and children with coarctation of the aorta

Design

Observational operative experience report

Authors

RTRoy L. TawesScottsdale Community CollegeEAEoin AberdeenUniversity of LondonDWDavid WaterstonUniversity of California, Irvine

Discussion

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Implication

Supports early operative correction of coarctation in infants and children; leaves open confirmation from randomized trials.

Study Design

Type

Observational (n=333)

Structured PICO

Does operative correction improve survival in infants and children with coarctation of the aorta?

P
Population
333 children with coarctation of the aorta, 54% under one year of age, undergoing operative correction.
E
Exposure
Operative correction
O
Outcome
Operative mortalityhard clinical

Early operative correction of coarctation of the aorta in infants and children is associated with low mortality in those over six months and can save nearly half of critically ill infants under six months.

Cite This Study

Tawes et al. (1969) conducted an observational in Coarctation of the Aorta (n=333). Operative correction was evaluated on Operative mortality. Operative correction of coarctation of the aorta had a 2.8% mortality in patients over six months of age and saved almost half of very ill infants under six months.

synapsesocial.com/papers/6ab7769488223941828eef24https://doi.org/10.1161/01.cir.39.5s1.i-173

Topics

Congenital heart disease adults
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Coarctation of the aorta in infancy and childhood.1976 · 115 citations
  2. 2Fifty-Three Cases of Coarctation of the Aorta1962 · 13 citations
  3. 3Coarctation of the aorta: review of 362 operated patients. Long-term follow-up and assessment of prognostic variables1987 · 119 citations
  4. 4Coarctation of the aorta: Current surgical management1985 · 6 citations
  5. 5Coarctation Of the Aorta1964 · 1 citations