Practical Aspects of Rate Adaptive Atrial (AAI,R) Pacing: Clinical Experiences in 44 Patients

Forty-four patients with sinus node disease and chronotropic incompetence but no evidence of AV conduction disturbances were treated with rate adaptive atrial (AAI,R) pacemakers. Medtronic Activitrax and Siemens Sensolog activity sensing single chamber pulse generators were used. Twenty-four patients (55%) had the bradycardia-tachycardia syndrome. The mean follow-up time is 20 +/- 14 months (range 1-48, median 17 months). All patients remain alive. Two patients were reoperated upon for lead problems without change of pacing mode. One patient developed symptomatic second-degree Wenckebach block during follow-up, and received a DDD,R system. Although 22 of the patients were treated with antiarrhythmic drugs postoperatively, no further cases of significant AV conduction disturbances were seen. During rapid atrial pacing, exercise-induced enhancement of AV conduction was a consistent finding, although less pronounced in patients treated with beta-blocking drugs. One patient developed permanent atrial fibrillation with an adequate ventricular rate. By systematic reprogramming procedures, QRS complex sensing through the atrial electrode could be demonstrated in 25 patients (23/28 with unipolar and 2/16 with bipolar leads). It could be counteracted effectively by pulse generator program selection in all cases. Forty-two of 44 patients (95%) remain in AAI,R pacing with normal function. Rate adaptive atrial pacing can be successfully applied in this patient group.