Treatment of Vascular Cognitive Impairment: A Bibliometric Analysis over a 12-Year Period

Purpose: The treatment of vascular cognitive impairment is a key point in the field of neuromedicine.Although a lot of research has been carried out, there are few bibliometric studies in this field.This article analyzes the main characteristics of the treatment of vascular cognitive impairment in the past 12 years, and can better contribute to the understanding of the emerging research trends and hotspots related to the treatment of vascular cognitive impairment.Methods: The authors searched for "vascular cognitive impairment" and "treatment" in articles in Web of Science Core Collection database from 2010 to 2022.We analyzed countries, institutions, journals, authors, references, and key words.Through CiteSpace version 6.1.R3 and VOSviewer version 1.6.18, the authors carried on the retrospective bibliometric analysis and draw the atlas.Results: A total of 1923 articles were published from 2010 to 2022.Neurology is the journal with the largest number of citations, while the United States, Capital Med Univ and WANGY are the countries, institutions and authors with the largest number of publications.The research hotspots are cerebral amyloid angiopathy, C-reactive protein, cerebral microvascular disease, blood-brain barrier, white matter lesions, amyloid β-peptide, cholinesterase inhibitors and so on.ConclusionEvery year, more and more articles are published in the treatment of vascular cognitive impairment and great progress has been made.The United States has made the most outstanding contribution in this important area.Cerebral amyloid angiopathy, C-reactive protein, cerebral microvascular disease, blood-brain barrier, white matter lesions, amyloid β-peptide, cholinesterase inhibitors are research hotspots.Neurovascular units, apoptosis, blood-brain barrier, Nf-kb, neuroinflammation may be the frontier of research.The focus of the treatment of vascular cognitive impairment is lifestyle changes, early intervention of vascular risk factors, and improvement of memory function.