Key result
Endurance treadmill training fails to alter cardiac myosin ATPase activity in dogs.
Why the study?
The sub-cellular phenomena accompanying the augmented myocardial function after endurance exercise training in animal models were not yet explained, specifically whether myosin ATPase activity increases.
Does endurance conditioning increase myocardial myosin ATPase activity in dogs?
Comparison
Endurance training by treadmill running vs no training
Design
Preclinical study
Follow-up
10 weeks
Authors
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No effect on canine cardiac myosin ATPase; leaves open relevance to other species or humans.
Does endurance conditioning increase myocardial myosin ATPase activity in dogs?
p-value: p=NS
Ten weeks of endurance training in dogs does not significantly alter cardiac muscle myosin ATPase activity, despite evidence of physical conditioning.
Carey et al. (1979) studied this question. Endurance exercise training (treadmill running) vs. Control (no training) was evaluated on Maximum myosin ATPase activity in cardiac muscle (p=NS). Ten weeks of endurance conditioning induced by treadmill running did not significantly affect cardiac muscle myosin ATPase activity in dogs.
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