Key result
Adding surgical ventricular restoration to CABG shows no long-term benefit over CABG alone.
Why the study?
Optimal treatment for patients with ischemic heart disease and severe left ventricular dysfunction remains debatable, with limited large-scale trial data available.
Does coronary artery bypass grafting with surgical ventricular restoration improve outcomes compared to coronary artery bypass grafting with optimal medical treatment in patients with ischemic heart disease and severe left ventricular dysfunction?
Does coronary artery bypass grafting with surgical ventricular restoration improve outcomes compared to coronary artery bypass grafting with optimal medical treatment in patients with ischemic heart disease and severe left ventricular dysfunction?
This review discusses the 10-year follow-up data from the STICH trial and its relevance to modern clinical practice for patients with ischemic heart disease and severe LV dysfunction.
Long-term STICH insights may guide individualized decisions in severe ischemic LV dysfunction; leaves open optimal SVR selection for prospective validation.
Optimal treatment for patients with ischemic heart disease and severe left ventricular dysfunction is a debatable subject in the literature. The largest and only trial on the subject so far is the Surgical Treatment for Ischemic Heart Failure trial. This trial compared coronary artery bypass grafting with optimal medical treatment in one arm versus coronary artery bypass grafting with surgical ventricular restoration in the second arm. Recently, the 10-year follow-up data of various subsets of the trial have been published. This study reviews various pertinent clinical issues related to the trial and its sub-studies and their relevance in routine modern-day clinical practice.
No takes yet. Share an insight, caveat, or question.
Imran Khan (2020) conducted a review in Ischemic heart disease and severe left ventricular dysfunction. Coronary artery bypass grafting with surgical ventricular restoration vs. Coronary artery bypass grafting with optimal medical treatment was evaluated. This review of the Surgical Treatment for Ischemic Heart Failure trial discusses 10-year follow-up data comparing CABG with or without surgical ventricular restoration for ischemic heart disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: