Key result
Relay 294-03 pacemaker sensor demonstrates highly reproducible rate response, peaking at 3 Hz in vitro.
Why the study?
The characteristics and performance of the sensor and rate adaptive algorithm in a new dual chamber rate responsive pacemaker were evaluated in vitro.
In vitro testing demonstrates that the Relay 294-03 pacemaker effectively uses an accelerometer sensitive to low-frequency motion, primarily in the anteroposterior direction, with excellent reproducibility.
In vitro data warrant caution before clinical use; leaves open whether sensor performance will translate to appropriate rate response in patients.
UNLABELLED: The characteristics of the sensor and rate adaptive algorithm included in a new dual chamber rate responsive pacemaker (Relay 294-03, Intermedics, Inc.) were studied by submitting the device to calibrated to-and-fro movements of specific frequencies and peak accelerations by means of a mechanical arm connected to a speed adapter. Atrial pacing rate was continuously recorded on a Holter monitor. The influences of the frequency, the magnitude, and the axis of the acceleration forces as well as the reproducibility of the rate response were evaluated. RESULTS: (1) The sensor was sensitive to frequencies ranging from 0.5 to 7 Hz with a peak sensitivity at 3 Hz; (2) the pacing rate was not affected during movements at frequencies > 6 Hz, commonly presented as nonactivity related signals (car, bus transportation, drilling....); (3) the pacing rate increased as a function of the acceleration magnitude up to 0.5 G (0.3 G for 3 Hz), then remained constant. This level of acceleration usually corresponds to high degrees of activity; (4) rate response was maximum when acceleration was directed in the anteroposterior direction; (5) reproducibility of the rate response was excellent (R2: 0.999; slope of the regression line: 0.999). CONCLUSION: Relay 294-03 is a low frequency signal sensing rate modulated pacemaker using an accelerometer sensitive to motion, mainly in the anteroposterior direction.
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Mahaux et al. (1992) studied this question. Relay 294-03 dual chamber rate responsive pacemaker was evaluated on Sensor sensitivity to acceleration forces and reproducibility of rate response. In vitro testing of the Relay 294-03 pacemaker sensor showed sensitivity to frequencies from 0.5 to 7 Hz (peak at 3 Hz) and excellent reproducibility of the rate response (R2: 0.999).
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