Key result
IABP reduces the severity of left ventricular failure in post-MI canine models.
Why the study?
The effects of intra-aortic balloon pump counterpulsation on cardiac performance in left ventricular failure due to coronary insufficiency were not well characterized in conscious intact models.
Key points are not available for this paper at this time.
Population
Intact conscious dogs with healing anterior myocardial infarcts and severe left ventricular failure
Comparison
With versus without intra-aortic balloon pump counterpulsation
Design
Experimental study in animal model
Hypothesis-generating for IABP in post-MI LV failure; prospective human trials needed before clinical adoption.
In intact conscious dogs with healing anterior myocardial infarcts due to left anterior descending coronary artery occlusion, severe left ventricular failure was produced by constricting the circumflex vessel. In this preparation intra-aortic balloon counterpulsation effectively reduced the degree of failure present.
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Hood et al. (1971) studied this question. Intra-aortic balloon counterpulsation effectively reduced the severity of left ventricular failure in conscious dogs with healing myocardial infarcts and induced coronary insufficiency.
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