Hepatic Transaminase’s Level in Chronically Treated Diabetic’s Patients (Type 2) at-Alhusain Teaching Hospital in Al- Nasiriyah City

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Background: The study was planned to evaluate the liver function of Type 2 Diabetes Mellitus (T2MD) by measuring Serum Glutamic Oxaloacetic Transaminase (SGOT), Serum Glutamic Pyruvic Transaminase (SGPT), plasma glucose, urea and creatinine.The study investigates the level of SGPT and SGOT in patients who suffer from diabetes mellitus at Al-Hussein teaching hospital in Al-nasiriyah city.Materials and methods: 80 patients who diagnosed as type 2diabetes mellitus (T2DM) (40 males and 40 females) were included in the study.Forty matched normal individuals were taken as a controlled group.Their age ranged between 40 and 90 years.Results: In the present study, mean values of SGPT, SGOT, plasma glucose, urea and creatinine were significantly higher in patients than in the controlled group (P<0.01), and this significant deference's found between the two groups of patients (P <0.01),The mean (± S.D.) SGOT in the controlled group was 25.01±0.77,whereas in T2DM (40-60 years) was 37.87± 3.88 and T2DM (60-90 years) was 53.73 ± 5.05.The mean (± S.D) blood sugar in controlled group was 92.24 ± 2.15, whereas in T2DM (40-60 years) was246.12± 16.23 and 387.00 ± 18.55 in the T2DM (60-90 years) .Creatinine levels in controlled groupwere0.82 ± 0.35 and in T2DM (40-60 years) was1.50 ± 0.98 and T2DM (60-90 years) was 2.03 ± 1.10.There was a significant increase in the SGPT, SGOT, plasma glucose, urea and creatinine in T2DM (60-90 years) compared with T2DM (40-60 years). Conclusion:The values of the liver function tests in patients with T2DM were significantly higher than that of controlled patients.Moreover, patients had higher glucose, urea and creatinine than in the controlled group.