Key result
Prototype TAVR prosthesis matches clinical bioprosthesis hydrodynamic performance with comparable transvalvular gradients.
Why the study?
The study was motivated by the need to evaluate the hydrodynamic function of a minimally invasive transcatheter aortic valve prosthesis prototype under physiological flow conditions.
Supports prototype development; leaves open in vivo performance and clinical translation.
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Ovcharenko et al. (2016) studied Aortic valve prosthesis evaluation. Prototype transcatheter aortic valve prosthesis vs. 3F Enable bioprosthesis was evaluated on Transprosthesis pressure gradient (mmHg) (p=0.37). The prototype transcatheter aortic valve prosthesis demonstrated hydrodynamic performance comparable to a clinical seamless bioprosthesis, with a mean transprosthesis pressure gradient of 18.01 mmHg versus 19.72 mmHg (p=0.37).
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