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Immunologic studies were performed in 9 patients with TAKAYASU'S arteritis. 1. γG immunoglobulin was increased in all of the 8 cases studied. 2. Circulating antibodies against the outer layer of the aorta and pulmonary artery were demonstrated in 7 cases among 9 cases by BOY-DEN's hemoagglutination reaction. 3. The specificity of this antigen-antibody reaction was confirmed by the hemoagglutination inhibition reaction and the anti human-r-globulin consumption test. 4. From these immunologic findings it is suggested that autoimmune mechanisms may participate in the developement of TAKAYASU'S arteritis.
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Masao Ikeda (1966) studied this question.
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