Key result
NT-proBNP and clinical risk scores optimize 10-year incident heart failure prediction in primary care.
Why the study?
A simple and effective heart failure risk score is needed to facilitate primary prevention and early diagnosis of HF in general practice.
Key points are not available for this paper at this time.
Comparison
Existing HF risk scores and optimized 10-year HF risk function with biomarkers
Design
External validation and optimization study
Follow-up
10 years
ARIC HF risk score with NT-proBNP improves prediction; leaves open whether implementation changes primary-care prevention.
A simple and effective heart failure (HF) risk score would facilitate the primary prevention and early diagnosis of HF in general practice. We examined the external validity of existing HF risk scores, optimized a 10-year HF risk function, and examined the incremental value of several biomarkers, including N-terminal pro-brain natriuretic peptide.
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Quibrera et al. (2020) studied this question. Heart failure risk scores and biomarkers including NT-proBNP were evaluated to optimize a 10-year predictive function for incident heart failure in general practice.
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