Key result
Diabetes shows no significant association with lower 10-year survival in hypertensive patients.
Why the study?
Survival differences between diabetic hypertensive patients, nondiabetic hypertensives, and the general population were unclear.
Cohort (n=673)
Diabetic hypertensives may face excess mortality risk; leaves open whether diabetes independently worsens hypertension prognosis.
Seventy-nine of 673 patients attending a hypertensive outpatient clinic were classified as diabetics at the first examination. These patients were age- and sex-matched to two control groups: nondiabetic hypertensives and the background population. Nondiabetic hypertensive patients had a significantly poorer survival than expected during a 10-year observation period; the survival of diabetic hypertensives was even poorer, although not significantly. No sex difference was observed in the survival rates of hypertensive diabetics, neither was a difference seen between insulin-dependent and non-insulin-dependent patients. Acute myocardial infarction was the most frequent cause of death in both diabetic (40%) and nondiabetic (42%) hypertensive persons.
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Thygesen et al. (1985) conducted a cohort in Hypertension and Diabetes Mellitus (n=673). Diabetes mellitus vs. Nondiabetic hypertension and background population was evaluated on Survival. Diabetic hypertensive patients experienced poorer 10-year survival compared to nondiabetic hypertensives, although not significantly, with myocardial infarction as the leading cause of death.
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