Key result
Inotropes and guideline-directed therapy achieve full recovery in hepatitis E-induced fulminant myocarditis with cardiogenic shock.
Why the study?
Cardiac involvement in acute hepatitis E infection is extremely rare and may be life-threatening, requiring early cardiac evaluation.
Case Report (n=1)
No
This case highlights that acute hepatitis E can rarely present with life-threatening fulminant myocarditis and cardiogenic shock, emphasizing the need for early cardiac evaluation in these patients.
Warrants cardiac evaluation in severe hepatitis E with shock; extends rare case reports but leaves management implications open.
Hepatitis E virus infection is endemic in Nepal and commonly presents as an acute self-limiting hepatitis. Cardiac involvement is extremely rare and may be life-threatening. We report a case of a young female who presented with fever, jaundice, progressive dyspnea and hypotension. Laboratory assessment confirmed acute hepatitis E infection. Chest radiography revealed cardiomegaly with bilateral pulmonary infiltrates. Transthoracic echocardiography demonstrated left ventricular dysfunction. Other infectious causes of myocarditis were excluded. The patient improved with inotropic support, heart failure treatment and other supportive management, with complete clinical recovery on follow-up. This case highlights the importance of early cardiac evaluation in patients with acute hepatitis E with features of heart failure.
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Bhatta et al. (2026) conducted a case report in Acute hepatitis E with fulminant myocarditis and cardiogenic shock (n=1). Inotropic support and heart failure treatment was evaluated. Inotropic support and heart failure treatment led to complete clinical recovery in a young female patient presenting with acute hepatitis E complicated by fulminant myocarditis and cardiogenic shock.
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