Key result
Low DASI functional activity links to ~12-point worse quality of life-12 quality of life.
Why the study?
The role of the Duke Activity Status Index (DASI) in assessing quality of life in patients with AF and acute decompensation of chronic heart failure remained to be evaluated.
Does the Duke Activity Status Index (DASI) identify worse quality-of-life parameters in patients with atrial fibrillation hospitalized for acute decompensation of chronic heart failure?
Cohort (n=151)
No
Does the Duke Activity Status Index (DASI) identify worse quality-of-life parameters in patients with atrial fibrillation hospitalized for acute decompensation of chronic heart failure?
In patients with atrial fibrillation hospitalized for acute decompensated heart failure, the Duke Activity Status Index (DASI) effectively identifies individuals with severely impaired functional capacity (0-20%) who experience significantly worse quality of life as measured by KCCQ-12 and MLHFQ.
Answers are grounded in this paper and cite their sources.
Low DASI may flag HF patients needing QoL support; leaves open whether activity interventions improve outcomes.
To evaluate the role of the DASI index in quality-of-life assessment in patients with atrial fibrillation (AF) and acute decompensation of chronic heart failure.
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Tolkacheva et al. (2026) conducted a cohort in Nonvalvular atrial fibrillation and acute decompensation of chronic heart failure (n=151). Low Duke Activity Status Index (DASI 0-20%) vs. Reduced (DASI 21-40%) and average (DASI 41-60%) functional activity was evaluated on Quality of life domain score on the Kansas City Cardiomyopathy Questionnaire (KCCQ-12) (p=<0.001). Low DASI functional activity was associated with worse quality of life-12 quality of life and MLHFQ scores than higher DASI groups.
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