August 2, 2025

Supplementary Fig.S4 from Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients

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Main finding shows that early clonal mutations vary significantly between smokers and non-smokers.
Key evidence indicates a distinct evolutionary trajectory of lung adenocarcinoma among different smoking statuses.
Approach involved analyzing mutation timing among male and female patients with lung adenocarcinoma.
Significance lies in understanding how smoking impacts the evolution of lung adenocarcinoma, informing prevention strategies.

Implication

This analysis compares early clonal mutations in smokers and non-smokers, suggesting key differences in lung adenocarcinoma evolution.

Comparison of the ratio of early clonal mutations between smokers and non-smokers among males and females respectively.

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Qin et al. (2025) studied this question.

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This analysis compares early clonal mutations in smokers and non-smokers, suggesting key differences in lung adenocarcinoma evolution.

Comparison of the ratio of early clonal mutations between smokers and non-smokers among males and females respectively.