August 2, 2025

Supplementary Fig.S19 from Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients

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MAIN FINDING: Smoking pack years are associated with an increased number of mutations in lung adenocarcinoma.
KEY EVIDENCE: A linear regression analysis shows a direct correlation between smoking history and mutation count.
APPROACH: The study examines the mutational landscape in lung adenocarcinoma among Chinese patients.
SIGNIFICANCE: Understanding mutation timing can reveal insights into the cancer's evolutionary trajectory and help guide prevention efforts.

Implication

Linear regression links smoking pack years to the number of mutations in lung adenocarcinoma, indicating a significant relationship.

Linear regression of smoking pack years with the number of smoking-related mutations and smoking-related early clonal mutations.

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Qin et al. (2025) studied this question.

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Linear regression links smoking pack years to the number of mutations in lung adenocarcinoma, indicating a significant relationship.

Linear regression of smoking pack years with the number of smoking-related mutations and smoking-related early clonal mutations.