August 2, 2025

Supplementary Fig.S8 from Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients

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Somatic mutations play a critical role in the evolution of lung adenocarcinoma among Chinese patients.
The study utilized a negative binomial mixed-effect model to analyze data across populations.
Findings indicate a non-linear relationship between tumor mutational burden and smoking pack years.
The results contribute valuable insights into the evolutionary trajectory of lung cancer related to smoking habits.

Implication

Negative binomial mixed-effect model reveals link between tumor mutational burden and smoking in East Asian and European populations.

Abstract

Negative binomial mixed-effect model to test the non-linearity between tumor mutational burden (TMB) and smoking pack years in both East Asian and TCGA European populations.

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Cite This Study

Qin et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d01c2 https://doi.org/10.1158/0008-5472.29760706

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Implication

Negative binomial mixed-effect model reveals link between tumor mutational burden and smoking in East Asian and European populations.

Abstract

Negative binomial mixed-effect model to test the non-linearity between tumor mutational burden (TMB) and smoking pack years in both East Asian and TCGA European populations.

Supplementary Fig.S8 from Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplementary Fig.S8 from Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients

Key Points

Implication

Abstract

Discussion

Cite This Study

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