August 2, 2025

Supplementary Fig.S5 from Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients

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MAIN FINDING: The study identifies a correlation between tumor mutational burden and smoking pack years in lung adenocarcinoma.
KEY EVIDENCE: Results show a significant linear relationship, suggesting how smoking influences mutational patterns in tumors.
APPROACH: Linear regression was applied to analyze data from the Nanjing-Huaxi Lung Cancer Cohort.
SIGNIFICANCE: Understanding mutation timing and burden helps elucidate the evolutionary trajectory of lung adenocarcinoma.

Implication

Linear regression analysis links tumor mutational burden and smoking history in lung adenocarcinoma patients, indicating significant correlations.

Linear regression analysis of the tumor mutational burden (TMB) and smoking pack years in the Nanjing-Huaxi Lung Cancer Cohort.

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Qin et al. (2025) studied this question.

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Linear regression analysis links tumor mutational burden and smoking history in lung adenocarcinoma patients, indicating significant correlations.

Linear regression analysis of the tumor mutational burden (TMB) and smoking pack years in the Nanjing-Huaxi Lung Cancer Cohort.