Supplementary Figure S20 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

MAIN FINDING: Single-cell eQTL mapping identifies subtype-specific genetic control in colorectal cancer.
KEY EVIDENCE: The analysis highlights distinct genetic influences across various cell subtypes in tumor tissues.
APPROACH: The study utilized supplementary figure data to characterize eQTLs specific to different cell types.
SIGNIFICANCE: Understanding genetic mechanisms in malignant transformation aids targeted therapies for colorectal cancer.

Single-cell eQTL mapping characterizes genetic control in colorectal cancer subtypes, suggesting specific pathways in malignant transformation.

Supplementary Figure 20 shows characterization of sc-eQTLs across cell subtypes in colorectal cancer tissues.

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Chen et al. (2025) studied this question.

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