Supplementary Figure S2 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

Major finding reveals the unique genetic control mechanisms tied to specific cell subtypes in colorectal cancer.
Data indicates differential proportions of major cell types across various stages of malignant transformation.
Approach utilized single-cell eQTL mapping to identify genetic influences on cell behavior in cancer tissues.
This research enhances understanding of how genetic differences affect cancer progression, aiding targeted therapies.

Single-cell eQTL mapping highlights cell subtype-specific genetic controls in malignant transformation of colorectal cancer.

Supplementary Figure 2 shows the differential proportion of each major cell type across multistage tissues.

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Chen et al. (2025) studied this question.

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