Supplementary Figure S13 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Can Chen; Yimin Cai; Wenlong Hu; Kai Tan; Zequn Lu; Xuanyu Zhu; Ziying Liu; Chunyi He; Guangping Xu; Ruizhe Zhang; Caibo Ning; Shuheng Ruan; Jiayan Gao; Xiaojun Yang; Yongchang Wei; Xu Zhu; Xiangpan Li; Faxi Wang; Fubing Wang; Jiaoyuan Li; Meng Jin; Bin Li; Ying Zhu; Jianbo Tian; Xiaoping Miao

doi:10.1158/2159-8290.29819685

Key Points

MAIN FINDING: The analysis highlights the specific genetic control of immune cell subtypes in colorectal cancer.
KEY EVIDENCE: Supplementary Figure 13 illustrates distribution changes of immune cell subtypes across various tissues.
APPROACH: The study uses single-cell eQTL mapping to investigate genetic mechanisms in malignant transformation.
SIGNIFICANCE: These findings advance understanding of genetic controls in cancer development and subtype behavior.

Implication

Single-cell eQTL mapping reveals immune cell subtype distribution changes in colorectal cancer, suggesting specific genetic controls in cancer progression.

Abstract

Supplementary Figure 13 shows the distribution changes of immune cell subtypes across multistage tissues.

Discussion

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Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/689a0f86e6551bb0af8d093f https://doi.org/10.1158/2159-8290.29819685

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Supplementary Figure S13 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

Supplementary Figure S13 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

Implication

Abstract

Discussion

Cite This Study

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