Supplementary Figure S12 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

MAIN FINDING: Single-cell eQTL mapping highlights unique genetic controls in specific cancer subtypes.
KEY EVIDENCE: Immune cell subsets are distinctly marked in the analysis, showcasing their role in malignancy.
APPROACH: The study employs single-cell techniques to analyze genetic factors driving colorectal cancer transformation.
SIGNIFICANCE: Understanding genetic control in cancer can lead to improved targeted therapies for specific cancer types.

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Single-cell eQTL mapping reveals subtype-specific genetic mechanisms in colorectal cancer, indicating immune cell roles.

Supplementary Figure 12 shows cell markers of immune cell subsets.

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Chen et al. (2025) studied this question.

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