Supplementary Figure S10 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

MAIN FINDING: The findings illustrate subtype-specific genetic mechanisms in the malignant transformation of colorectal cancer.
KEY EVIDENCE: Supplementary Figure 10 depicts markers and the changing proportions of endothelial cell subsets in tumors.
APPROACH: The research used single-cell eQTL mapping to investigate gene regulation pathways in colorectal cancer.
SIGNIFICANCE: This work improves understanding of cancer genetics and could inform targeted therapies for colorectal cancer.

Single-cell eQTL mapping reveals distinct genetic control mechanisms in colorectal cancer, highlighting endothelial cell subset variations.

Supplementary Figure 10 shows cell markers and differential proportions of endothelial cell subsets.

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Chen et al. (2025) studied this question.

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