Supplementary Figure S15 from Single-cell eQTL Mapping Reveals Cell Subtype–specific Genetic Control and Mechanism in Malignant Transformation of Colorectal Cancer

Key Points

Supplementary Figure 15 illustrates expression profiles of B cells during colorectal cancer development.
The mapping highlights cell subtype-specific genetic control throughout different cancer stages.
Research utilized single-cell analysis to uncover mechanisms driving malignant transformation.
Findings may enhance understanding of genetic factors in colorectal cancer progression and treatment.

Single-cell eQTL mapping reveals specific genetic control for B cells in colorectal cancer, suggesting distinct transformation mechanisms.

Supplementary Figure 15 shows the expression profiles of B cells in different stages of colorectal cancer development.

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Chen et al. (2025) studied this question.

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